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polι, a remarkably error-prone human DNA polymerase

The Saccharomyces cerevisiae RAD30 gene encodes DNA polymerase η. Humans possess two Rad30 homologs. One (RAD30A/POLH) has previously been characterized and shown to be defective in humans with the Xeroderma pigmentosum variant phenotype. Here, we report experiments demonstrating that the second hum...

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Udgivet i:Genes Dev
Principais autores: Tissier, Agnès, McDonald, John P., Frank, Ekaterina G., Woodgate, Roger
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316739/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10887158/
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