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polι, a remarkably error-prone human DNA polymerase
The Saccharomyces cerevisiae RAD30 gene encodes DNA polymerase η. Humans possess two Rad30 homologs. One (RAD30A/POLH) has previously been characterized and shown to be defective in humans with the Xeroderma pigmentosum variant phenotype. Here, we report experiments demonstrating that the second hum...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Cold Spring Harbor Laboratory Press
2000
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316739/ https://ncbi.nlm.nih.gov/pubmed/10887158 |
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