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polι, a remarkably error-prone human DNA polymerase

The Saccharomyces cerevisiae RAD30 gene encodes DNA polymerase η. Humans possess two Rad30 homologs. One (RAD30A/POLH) has previously been characterized and shown to be defective in humans with the Xeroderma pigmentosum variant phenotype. Here, we report experiments demonstrating that the second hum...

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書目詳細資料
Main Authors: Tissier, Agnès, McDonald, John P., Frank, Ekaterina G., Woodgate, Roger
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC316739/
https://ncbi.nlm.nih.gov/pubmed/10887158
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