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Altered nucleotide misinsertion fidelity associated with polι-dependent replication at the end of a DNA template
A hallmark of human DNA polymerase ι (polι) is the asymmetric fidelity of replication at template A and T when the enzyme extends primers annealed to a single-stranded template. Here, we report on the efficiency and accuracy of polι-dependent replication at a nick, a gap, the very end of a template...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2001
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125476/ https://ncbi.nlm.nih.gov/pubmed/11387224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2914 |
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