Altered nucleotide misinsertion fidelity associated with polι-dependent replication at the end of a DNA template
A hallmark of human DNA polymerase ι (polι) is the asymmetric fidelity of replication at template A and T when the enzyme extends primers annealed to a single-stranded template. Here, we report on the efficiency and accuracy of polι-dependent replication at a nick, a gap, the very end of a template...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2914 |
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