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Altered nucleotide misinsertion fidelity associated with polι-dependent replication at the end of a DNA template
A hallmark of human DNA polymerase ι (polι) is the asymmetric fidelity of replication at template A and T when the enzyme extends primers annealed to a single-stranded template. Here, we report on the efficiency and accuracy of polι-dependent replication at a nick, a gap, the very end of a template...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125476/ https://ncbi.nlm.nih.gov/pubmed/11387224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2914 |
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