Altered nucleotide misinsertion fidelity associated with polι-dependent replication at the end of a DNA template

A hallmark of human DNA polymerase ι (polι) is the asymmetric fidelity of replication at template A and T when the enzyme extends primers annealed to a single-stranded template. Here, we report on the efficiency and accuracy of polι-dependent replication at a nick, a gap, the very end of a template...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Frank, Ekaterina G., Tissier, Agnès, McDonald, John P., Rapić-Otrin, Vesna, Zeng, Xianmin, Gearhart, Patricia J., Woodgate, Roger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2914
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