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The phosphatase calcineurin regulates pathological TDP-43 phosphorylation
Detergent insoluble inclusions of TDP-43 protein are hallmarks of the neuropathology in over 90% of amyotrophic lateral sclerosis (ALS) cases and approximately half of frontotemporal dementia (FTLD-TDP) cases. In TDP-43 proteinopathy disorders, lesions containing aggregated TDP-43 protein are extens...
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Publicado no: | Acta Neuropathol |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026939/ https://ncbi.nlm.nih.gov/pubmed/27473149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1600-y |
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