Wird geladen...

Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency

IFN responses control acute HSV infection, but their role in regulating HSV latency is poorly understood. To address this we used mice lacking IFN signaling specifically in neural tissues. These mice supported a higher acute viral load in nervous tissue and delayed establishment of latency. While la...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Virology
Hauptverfasser: Rosato, Pamela C., Katzenell, Sarah, Pesola, Jean M., North, Brian, Coen, Donald M., Leib, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026629/
https://ncbi.nlm.nih.gov/pubmed/27518540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.06.016
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!