Nature and duration of growth factor signaling through receptor tyrosine kinases regulates HSV-1 latency in neurons

Herpes simplex virus-1 (HSV-1) establishes lifelong latency in peripheral neurons where productive replication is suppressed. While periodic reactivation results in virus production, the molecular basis of neuronal latency remains incompletely understood. Using a primary neuronal culture system of H...

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Bibliographische Detailangaben
Hauptverfasser: Camarena, Vladimir, Kobayashi, Mariko, Kim, Ju Youn, Roehm, Pamela, Perez, Rosalia, Gardner, James, Wilson, Angus C., Mohr, Ian, Chao, Moses V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988476/
https://ncbi.nlm.nih.gov/pubmed/20951966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.09.007
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