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Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons

Herpes simplex virus 1 (HSV-1) establishes lifelong infection in the neurons of trigeminal ganglia (TG), cycling between productive infection and latency. Neuronal antiviral responses are driven by type I interferon (IFN) and are crucial to controlling HSV-1 virulence. Autophagy also plays a role in...

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Pubblicato in:J Virol
Autori principali: Katzenell, Sarah, Leib, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836354/
https://ncbi.nlm.nih.gov/pubmed/26912623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02908-15
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