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Neuronal Interferon Signaling Is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis

Interferon (IFN) responses are critical for controlling herpes simplex virus 1 (HSV-1). The importance of neuronal IFN signaling in controlling acute and latent HSV-1 infection remains unclear. Compartmentalized neuron cultures revealed that mature sensory neurons respond to IFNβ at both the axon an...

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Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Rosato, Pamela C., Leib, David A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495997/
https://ncbi.nlm.nih.gov/pubmed/26153886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005028
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