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Intrinsic Innate Immunity Fails To Control Herpes Simplex Virus and Vesicular Stomatitis Virus Replication in Sensory Neurons and Fibroblasts

Herpes simplex virus 1 (HSV-1) establishes lifelong latent infections in the sensory neurons of the trigeminal ganglia (TG), wherein it retains the capacity to reactivate. The interferon (IFN)-driven antiviral response is critical for the control of HSV-1 acute replication. We therefore sought to fu...

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Hlavní autoři: Rosato, Pamela C., Leib, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136337/
https://ncbi.nlm.nih.gov/pubmed/24942587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01462-14
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