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Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency
IFN responses control acute HSV infection, but their role in regulating HSV latency is poorly understood. To address this we used mice lacking IFN signaling specifically in neural tissues. These mice supported a higher acute viral load in nervous tissue and delayed establishment of latency. While la...
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| Udgivet i: | Virology |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026629/ https://ncbi.nlm.nih.gov/pubmed/27518540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.06.016 |
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