A Neuron-Specific Host MicroRNA Targets Herpes Simplex Virus-1 ICP0 Expression and Promotes Latency

After infecting peripheral sites, herpes simplex virus (HSV) invades the nervous system and initiates latent infection in sensory neurons. Establishment and maintenance of HSV latency requires host survival, and entails repression of productive cycle (“lytic”) viral gene expression. We find that a n...

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Detalhes bibliográficos
Main Authors: Pan, Dongli, Flores, Omar, Umbach, Jennifer L., Pesola, Jean M., Bentley, Peris, Rosato, Pamela C., Leib, David A., Cullen, Bryan R., Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142646/
https://ncbi.nlm.nih.gov/pubmed/24721573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.03.004
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