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Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways
S-adenosyl-l-methionine (AdoMet) is an essential enzyme cosubstrate in fundamental biology with an expanding range of biocatalytic and therapeutic applications. We report the design, synthesis, and evaluation of stable, functional AdoMet isosteres that are resistant to the primary contributors to Ad...
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| Publicado en: | ACS Chem Biol |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026608/ https://ncbi.nlm.nih.gov/pubmed/27351335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00348 |
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