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Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways
S-adenosyl-l-methionine (AdoMet) is an essential enzyme cosubstrate in fundamental biology with an expanding range of biocatalytic and therapeutic applications. We report the design, synthesis, and evaluation of stable, functional AdoMet isosteres that are resistant to the primary contributors to Ad...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026608/ https://ncbi.nlm.nih.gov/pubmed/27351335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00348 |
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