Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart

Ceramide accumulation is known to accompany acute myocardial ischemia, but its role in the pathogenesis of ischemic heart disease is unclear. In this study, we aimed to determine how ceramides accumulate in the ischemic heart and to determine if cardiac function following ischemia can be improved by...

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Detaylı Bibliyografya
Yayımlandı:J Mol Cell Cardiol
Asıl Yazarlar: Klevstig, M, Ståhlman, M, Lundqvist, A, Scharin Täng, M, Fogelstrand, P, Adiels, M, Andersson, L, Kolesnick, R, Jeppsson, A, Borén, J, Levin, MC
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026316/
https://ncbi.nlm.nih.gov/pubmed/26930027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.02.019
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