Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230

Development of a Plasmodium falciparum (Pf) transmission blocking vaccine (TBV) has the potential to significantly impact malaria control. Antibodies elicited against sexual stage proteins in the human bloodstream are taken up with the blood meal of the mosquitoes and inactivate parasite development...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: MacDonald, Nicholas J., Nguyen, Vu, Shimp, Richard, Reiter, Karine, Herrera, Raul, Burkhardt, Martin, Muratova, Olga, Kumar, Krishan, Aebig, Joan, Rausch, Kelly, Lambert, Lynn, Dawson, Nikiah, Sattabongkot, Jetsumon, Ambroggio, Xavier, Duffy, Patrick E., Wu, Yimin, Narum, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025679/
https://ncbi.nlm.nih.gov/pubmed/27432885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732305
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