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Pfs230 yields higher malaria transmission–blocking vaccine activity than Pfs25 in humans but not mice
BACKGROUND: Vaccines that block human-to-mosquito Plasmodium transmission are needed for malaria eradication, and clinical trials have targeted zygote antigen Pfs25 for decades. We reported that a Pfs25 protein-protein conjugate vaccine formulated in alum adjuvant induced serum functional activity i...
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| Izdano u: | J Clin Invest |
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| Glavni autori: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011888/ https://ncbi.nlm.nih.gov/pubmed/33561016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI146221 |
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