Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230

Development of a Plasmodium falciparum (Pf) transmission blocking vaccine (TBV) has the potential to significantly impact malaria control. Antibodies elicited against sexual stage proteins in the human bloodstream are taken up with the blood meal of the mosquitoes and inactivate parasite development...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: MacDonald, Nicholas J., Nguyen, Vu, Shimp, Richard, Reiter, Karine, Herrera, Raul, Burkhardt, Martin, Muratova, Olga, Kumar, Krishan, Aebig, Joan, Rausch, Kelly, Lambert, Lynn, Dawson, Nikiah, Sattabongkot, Jetsumon, Ambroggio, Xavier, Duffy, Patrick E., Wu, Yimin, Narum, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025679/
https://ncbi.nlm.nih.gov/pubmed/27432885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732305
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