Enhanced antibody responses to Plasmodium falciparum Pfs28 induced in mice by conjugation to ExoProtein A of Pseudomonas aeruginosa with an improved procedure

In this paper we report our efforts to enhance the immunogenicity of Pfs28, a transmission blocking vaccine candidate of Plasmodium falciparum, using a strategy of chemical conjugation. With an improved procedure Pfs28 was covalently coupled to the mutant and nontoxic ExoProtein A of Pseudomonas aer...

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Detalhes bibliográficos
Main Authors: Qian, Feng, Aebig, Joan A., Reiter, Karine, Barnafo, Emma, Zhang, Yanling, Shimp, Richard L., Rausch, Kelly M., Jones, David S., Zhu, Daming, Lambert, Lynn, Mullen, Gregory E. D., Narum, David L., Miller, Louis H., Wu, Yimin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761608/
https://ncbi.nlm.nih.gov/pubmed/19146977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.12.009
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