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Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network
The ATP7A protein is a ubiquitous copper-transporting P-type ATPase that is mutated in the lethal pediatric disorder of copper metabolism, Menkes disease. The steady-state location of ATP7A is within the trans-Golgi network (TGN), where it delivers copper to copper-dependent enzymes within the secre...
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| Udgivet i: | Metallomics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025395/ https://ncbi.nlm.nih.gov/pubmed/27337370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mt00093b |
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