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Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells

REST (RE1-silencing transcription factor, also called Nrsf) is involved in the maintenance of the undifferentiated state of neuronal stem/progenitor cells in vitro by preventing precocious expression of neuronal genes. REST expression was then decreased in developing neurons to down-regulate neurona...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Aoki, Hitomi, Ogino, Hajime, Tomita, Hiroyuki, Hara, Akira, Kunisada, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025245/
https://ncbi.nlm.nih.gov/pubmed/27631609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163042
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