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Ectopic Activation of Wnt/β-Catenin Signaling in Lens Fiber Cells Results in Cataract Formation and Aberrant Fiber Cell Differentiation

The Wnt/β-catenin signaling pathway controls many processes during development, including cell proliferation, cell differentiation and tissue homeostasis, and its aberrant regulation has been linked to various pathologies. In this study we investigated the effect of ectopic activation of Wnt/β-caten...

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Detalhes bibliográficos
Main Authors: Antosova, Barbora, Smolikova, Jana, Borkovcova, Romana, Strnad, Hynek, Lachova, Jitka, Machon, Ondrej, Kozmik, Zbynek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813504/
https://ncbi.nlm.nih.gov/pubmed/24205179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078279
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