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Induced haploinsufficiency of Kit receptor tyrosine kinase impairs brain development
Kit receptor tyrosine kinase is highly expressed in the developing mammalian brain, yet little is known about its contribution to neural cell development and function. Here we introduced a brain-specific conditional Kit loss-of-function mutation in mice and observed severe hypoplasia of the central...
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| Publicado no: | JCI Insight |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841866/ https://ncbi.nlm.nih.gov/pubmed/28978807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94385 |
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