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Allosteric Communication across the Native and Mutated KIT Receptor Tyrosine Kinase
A fundamental goal in cellular signaling is to understand allosteric communication, the process by which signals originated at one site in a protein propagate dependably to affect remote functional sites. Here, we describe the allosteric regulation of the receptor tyrosine kinase KIT. Our analysis e...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426562/ https://ncbi.nlm.nih.gov/pubmed/22927810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002661 |
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