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Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract

Cell–cell interactions organize lens fiber cells into highly ordered structures to maintain transparency. However, signals regulating such interactions have not been well characterized. We report here that ephrin-A5, a ligand of the Eph receptor tyrosine kinases, plays a key role in lens fiber cell...

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Detalhes bibliográficos
Main Authors: Cooper, Margaret A., Son, Alexander I., Komlos, Daniel, Sun, Yuhai, Kleiman, Norman J., Zhou, Renping
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575469/
https://ncbi.nlm.nih.gov/pubmed/18948590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808987105
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