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Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract

Cell–cell interactions organize lens fiber cells into highly ordered structures to maintain transparency. However, signals regulating such interactions have not been well characterized. We report here that ephrin-A5, a ligand of the Eph receptor tyrosine kinases, plays a key role in lens fiber cell...

詳細記述

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書誌詳細
主要な著者: Cooper, Margaret A., Son, Alexander I., Komlos, Daniel, Sun, Yuhai, Kleiman, Norman J., Zhou, Renping
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575469/
https://ncbi.nlm.nih.gov/pubmed/18948590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808987105
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