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Breakdown of Interlocking Domains May Contribute to Formation of Membranous Globules and Lens Opacity in Ephrin-A5(−/−) Mice

Ephrin-A5, a ligand of the Eph family of receptor tyrosine kinases, plays a key role in lens fiber cell packing and cell-cell adhesion, with approximately 87% of ephrin-A5(−/−) mice develop nuclear cataracts. Here, we investigated the extensive formation of light-scattering globules associated with...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Biswas, Sondip, Son, Alexander, Yu, Qili, Zhou, Renping, Lo, Woo-Kuen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842153/
https://ncbi.nlm.nih.gov/pubmed/26643403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.11.017
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