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Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific qPCR

Establishing the KRAS mutational status of tumor samples is essential to manage patients with colorectal or lung cancer, since these mutations preclude treatment with monoclonal anti-epidermal growth factor receptor (EGFR) antibodies. We report an inexpensive, rapid multiplex allele-specific qPCR me...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Orue, Andrea, Rieber, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025196/
https://ncbi.nlm.nih.gov/pubmed/27632281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163070
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