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Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific qPCR
Establishing the KRAS mutational status of tumor samples is essential to manage patients with colorectal or lung cancer, since these mutations preclude treatment with monoclonal anti-epidermal growth factor receptor (EGFR) antibodies. We report an inexpensive, rapid multiplex allele-specific qPCR me...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025196/ https://ncbi.nlm.nih.gov/pubmed/27632281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163070 |
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