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miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington’s Disease Monkey Neural Cells

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the expansion of polyglutamine (polyQ) tract that leads to motor, cognitive and psychiatric impairment. Currently there is no cure for HD. A transgenic HD nonhuman primate (HD-NHP) model was developed with progressive dev...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kunkanjanawan, Tanut, Carter, Richard L., Prucha, Melinda S., Yang, Jinjing, Parnpai, Rangsun, Chan, Anthony W. S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025087/
https://ncbi.nlm.nih.gov/pubmed/27631085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162788
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