Reversal of Cellular Phenotypes in Neural Cells Derived from Huntington’s Disease Monkey-Induced Pluripotent Stem Cells

Huntington’s disease (HD) is a dominant neurodegenerative disorder caused by the expansion of glutamine residues in the N-terminal region of the huntingtin (HTT) protein. The disease results in progressive neuronal loss, leading to motor, cognitive, and psychiatric impairment. Here, we report the es...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Carter, Richard L., Chen, Yiju, Kunkanjanawan, Tanut, Xu, Yan, Moran, Sean P., Putkhao, Kittiphong, Yang, Jinjing, Huang, Anderson H.C., Parnpai, Rangsun, Chan, Anthony W.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223707/
https://ncbi.nlm.nih.gov/pubmed/25358787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.07.011
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