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miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington’s Disease Monkey Neural Cells

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the expansion of polyglutamine (polyQ) tract that leads to motor, cognitive and psychiatric impairment. Currently there is no cure for HD. A transgenic HD nonhuman primate (HD-NHP) model was developed with progressive dev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kunkanjanawan, Tanut, Carter, Richard L., Prucha, Melinda S., Yang, Jinjing, Parnpai, Rangsun, Chan, Anthony W. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025087/
https://ncbi.nlm.nih.gov/pubmed/27631085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162788
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