Pathogenic Cellular Phenotypes are Germline Transmissible in a Transgenic Primate Model of Huntington's Disease

A transgenic primate model for Huntington's Disease (HD) first reported by our group that (HD monkeys) carry the mutant Huntingtin (HTT) gene with expanded polyglutamine (CAG) repeats and, develop chorea, dystonia, and other involuntary motor deficiencies similar to HD [1]. More recently, we ha...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Putkhao, Kittiphong, Kocerha, Jannet, Cho, In-Ki, Yang, Jinjing, Parnpai, Rangsun, Chan, Anthony W.S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2013
Pynciau:
Original Research Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613972/
https://ncbi.nlm.nih.gov/pubmed/23190281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0469
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