Pathogenic Cellular Phenotypes are Germline Transmissible in a Transgenic Primate Model of Huntington's Disease

A transgenic primate model for Huntington's Disease (HD) first reported by our group that (HD monkeys) carry the mutant Huntingtin (HTT) gene with expanded polyglutamine (CAG) repeats and, develop chorea, dystonia, and other involuntary motor deficiencies similar to HD [1]. More recently, we ha...

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Bibliografiset tiedot
Päätekijät: Putkhao, Kittiphong, Kocerha, Jannet, Cho, In-Ki, Yang, Jinjing, Parnpai, Rangsun, Chan, Anthony W.S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2013
Aiheet:
Original Research Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613972/
https://ncbi.nlm.nih.gov/pubmed/23190281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0469
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