Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

We present the bottleneck sequencing system (BotSeqS), a next-generation sequencing method that simultaneously quantifies rare somatic point mutations across the mitochondrial and nuclear genomes. BotSeqS combines molecular barcoding with a simple dilution step immediately before library amplificati...

全面介紹

Na minha lista:
書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Hoang, Margaret L., Kinde, Isaac, Tomasetti, Cristian, McMahon, K. Wyatt, Rosenquist, Thomas A., Grollman, Arthur P., Kinzler, Kenneth W., Vogelstein, Bert, Papadopoulos, Nickolas
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024639/
https://ncbi.nlm.nih.gov/pubmed/27528664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607794113
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍