Thyroid hormone activation by type 2 deiodinase mediates exercise‐induced peroxisome proliferator‐activated receptor‐γ coactivator‐1α expression in skeletal muscle

KEY POINTS: In skeletal muscle, physical exercise and thyroid hormone mediate the peroxisome proliferator‐activated receptor‐γ coactivator‐1α (PGC‐1a) expression that is crucial to skeletal muscle mitochondrial function. The expression of type 2 deiodinase (D2), which activates thyroid hormone in sk...

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發表在:J Physiol
Main Authors: Bocco, Barbara M. L. C., Louzada, Ruy A. N., Silvestre, Diego H. S., Santos, Maria C. S., Anne‐Palmer, Elena, Rangel, Igor F., Abdalla, Sherine, Ferreira, Andrea C., Ribeiro, Miriam O., Gereben, Balázs, Carvalho, Denise P., Bianco, Antonio C., Werneck‐de‐Castro, João P.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Muscle
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023700/
https://ncbi.nlm.nih.gov/pubmed/27302464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272440
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