Thyroid hormone activation by type 2 deiodinase mediates exercise‐induced peroxisome proliferator‐activated receptor‐γ coactivator‐1α expression in skeletal muscle

KEY POINTS: In skeletal muscle, physical exercise and thyroid hormone mediate the peroxisome proliferator‐activated receptor‐γ coactivator‐1α (PGC‐1a) expression that is crucial to skeletal muscle mitochondrial function. The expression of type 2 deiodinase (D2), which activates thyroid hormone in sk...

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Udgivet i:J Physiol
Main Authors: Bocco, Barbara M. L. C., Louzada, Ruy A. N., Silvestre, Diego H. S., Santos, Maria C. S., Anne‐Palmer, Elena, Rangel, Igor F., Abdalla, Sherine, Ferreira, Andrea C., Ribeiro, Miriam O., Gereben, Balázs, Carvalho, Denise P., Bianco, Antonio C., Werneck‐de‐Castro, João P.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Muscle
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023700/
https://ncbi.nlm.nih.gov/pubmed/27302464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272440
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