Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function

Background: Myogenesis is positively regulated by thyroid hormone (triiodothyronine [T3]), which is amplified by the type 2 deiodinase (D2) activation of thyroxine to T3. Global inactivation of the Dio2 gene impairs skeletal muscle (SKM) differentiation and regeneration in response to muscle injury....

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Vydáno v:Thyroid
Hlavní autoři: Ignacio, Daniele L., Silvestre, Diego H. S., Anne-Palmer, Elena, Bocco, Barbara M. L. C., Fonseca, Tatiana L., Ribeiro, Miriam O., Gereben, Balázs, Bianco, Antonio C., Werneck-de-Castro, Joao P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2017
Témata:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385430/
https://ncbi.nlm.nih.gov/pubmed/27967605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2016.0392
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