Thyroid hormone activation by type 2 deiodinase mediates exercise‐induced peroxisome proliferator‐activated receptor‐γ coactivator‐1α expression in skeletal muscle

KEY POINTS: In skeletal muscle, physical exercise and thyroid hormone mediate the peroxisome proliferator‐activated receptor‐γ coactivator‐1α (PGC‐1a) expression that is crucial to skeletal muscle mitochondrial function. The expression of type 2 deiodinase (D2), which activates thyroid hormone in sk...

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Veröffentlicht in:J Physiol
Hauptverfasser: Bocco, Barbara M. L. C., Louzada, Ruy A. N., Silvestre, Diego H. S., Santos, Maria C. S., Anne‐Palmer, Elena, Rangel, Igor F., Abdalla, Sherine, Ferreira, Andrea C., Ribeiro, Miriam O., Gereben, Balázs, Carvalho, Denise P., Bianco, Antonio C., Werneck‐de‐Castro, João P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Muscle
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023700/
https://ncbi.nlm.nih.gov/pubmed/27302464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272440
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