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Phosphatidic acid sequesters Sec18p from cis-SNARE complexes to inhibit priming
Yeast vacuole fusion requires the activation of cis-SNARE complexes through priming carried out by Sec18p/NSF and Sec17p/α-SNAP. The association of Sec18p with vacuolar cis-SNAREs is regulated in part by phosphatidic acid (PA) phosphatase production of diacylglycerol (DAG). Inhibition of PA phosphat...
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| Udgivet i: | Traffic |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023487/ https://ncbi.nlm.nih.gov/pubmed/27364524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12423 |
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