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Copper blocks V-ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion

The accumulation of Copper in organisms can lead to altered functions of various pathways and become cytotoxic through the generation of reactive oxygen species. In yeast, cytotoxic metals such as Hg(+), Cd(2+), and Cu(2+) are transported into the lumen of the vacuole through various pumps. Copper i...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Miner, Gregory E., Sullivan, Katherine D., Zhang, Chi, Hurst, Logan R., Starr, Matthew L., Rivera-Kohr, David A., Jones, Brandon C., Guo, Annie, Fratti, Rutilio A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800785/
https://ncbi.nlm.nih.gov/pubmed/31368617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12683
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