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Copper blocks V-ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion
The accumulation of Copper in organisms can lead to altered functions of various pathways and become cytotoxic through the generation of reactive oxygen species. In yeast, cytotoxic metals such as Hg(+), Cd(2+), and Cu(2+) are transported into the lumen of the vacuole through various pumps. Copper i...
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| Publicado en: | Traffic |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800785/ https://ncbi.nlm.nih.gov/pubmed/31368617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12683 |
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