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Crystal Structure and Activity of Francisella novicida UDP-N-acetylglucosamine Acyltransferase
The first step of lipid A biosynthesis in Escherichia coli (E. coli) is catalyzed by LpxA (EcLpxA), an acyltransferase selective for UDP-N-acetylglucosamine (UDP-GlcNAc) and R-3-hydroxymyristoyl-acyl carrier protein (3-OH-C(14)-ACP), and is an essential step in majority of Gram-negative bacteria. Si...
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| Publicado en: | Biochem Biophys Res Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021990/ https://ncbi.nlm.nih.gov/pubmed/27545601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.08.098 |
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