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Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase
UDP-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (LpxA) catalyzes the first step of lipid A biosynthesis, the reversible transfer of the R-3-hydroxyacyl chain from R-3-hydroxyacyl acyl carrier protein to the glucosamine 3-OH group of UDP-GlcNAc. Escherichia coli LpxA is highly selective for R-3-...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1959417/ https://ncbi.nlm.nih.gov/pubmed/17698807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705833104 |
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