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Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide

UDP-GlcNAc acyltransferase (LpxA) catalyzes the first step of lipid A biosynthesis, the transfer of the R-3-hydroxyacyl chain from R-3-hydroxyacyl acyl carrier protein (ACP) to the glucosamine 3-OH group of UDP-GlcNAc. LpxA is essential for the growth of Escherichia coli and related Gram-negative ba...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Williams, Allison H., Immormino, Robert M., Gewirth, Daniel T., Raetz, Christian R. H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544142/
https://ncbi.nlm.nih.gov/pubmed/16835299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604465103
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