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Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide
UDP-GlcNAc acyltransferase (LpxA) catalyzes the first step of lipid A biosynthesis, the transfer of the R-3-hydroxyacyl chain from R-3-hydroxyacyl acyl carrier protein (ACP) to the glucosamine 3-OH group of UDP-GlcNAc. LpxA is essential for the growth of Escherichia coli and related Gram-negative ba...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544142/ https://ncbi.nlm.nih.gov/pubmed/16835299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604465103 |
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