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Structures of Bacteroides fragilis uridine 5′-diphosphate-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (BfLpxA)

Uridine 5′-diphosphate-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (LpxA) catalyzes a reversible reaction for adding an O-acyl group to the GlcNAc in UDP-GlcNAc in the first step of lipid A biosynthesis. Lipid A constitutes a major component of lipopolysaccharides, also referred to as endotoxin...

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Dettagli Bibliografici
Pubblicato in:Acta Crystallogr D Biol Crystallogr
Autori principali: Ngo, Alice, Fong, Kai T., Cox, Daniel L., Chen, Xi, Fisher, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427197/
https://ncbi.nlm.nih.gov/pubmed/25945572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715003326
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