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Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons

OBJECTIVE: The ventromedial hypothalamic nucleus (VMH) regulates energy balance and glucose homeostasis. Leptin and insulin exert metabolic effects via their cognate receptors expressed by the steroidogenic factor 1 (SF1) neurons within the VMH. However, detailed cellular mechanisms involved in the...

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Publicat a:Mol Metab
Autors principals: Sohn, Jong-Woo, Oh, Youjin, Kim, Ki Woo, Lee, Syann, Williams, Kevin W., Elmquist, Joel K.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021675/
https://ncbi.nlm.nih.gov/pubmed/27656404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.06.004
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