Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin

The dogma that life without insulin is incompatible has recently been challenged by results showing viability of insulin-deficient rodents undergoing leptin mono-therapy. Yet, the mechanisms underlying these actions of leptin are unknown. Here, the metabolic outcomes of intracerebroventricular (icv)...

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Detalhes bibliográficos
Main Authors: Fujikawa, Teppei, Berglund, Eric D., Patel, Vishal R., Ramadori, Giorgio, Vianna, Claudia R., Vong, Linh, Thorel, Fabrizio, Chera, Simona, Herrera, Pedro L., Lowell, Bradford B., Elmquist, Joel K., Baldi, Pierre, Coppari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890693/
https://ncbi.nlm.nih.gov/pubmed/24011077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.08.004
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