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The Acute Effects of Leptin Require PI3K Signaling in the Hypothalamic Ventral Premammillary Nucleus

Evidence suggests that the role played by the adipocyte-derived hormone leptin in female reproductive physiology is mediated in part by neurons located within the ventral premammillary nucleus (PMV). Leptin activates PMV neurons; however, the intracellular signaling pathway and channel(s) involved r...

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Autores principales: Williams, Kevin W., Sohn, Jong-Woo, Donato, Jose, Lee, Charlotte E., Zhao, Jean J., Elmquist, Joel K., Elias, Carol F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319415/
https://ncbi.nlm.nih.gov/pubmed/21917798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2602-11.2011
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