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PI3K signalling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis

Phosphatidyl inositol 3-kinase (PI3K) signalling in the hypothalamus has been implicated in the regulation of energy homeostasis, but the critical brain sites where this intracellular signal integrates various metabolic cues to regulate food intake and energy expenditure are unknown. Here we show th...

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Detalhes bibliográficos
Main Authors: Xu, Yong, Hill, Jennifer W., Fukuda, Makoto, Gautron, Laurent, Sohn, Jong-Woo, Kim, Ki-Woo, Lee, Charlotte E., Choi, Michelle J., Lauzon, Danielle, Dhillon, Harveen, Lowell, Bradford B., Zigman, Jeffrey M., Zhao, Jean J., Elmquist, Joel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919367/
https://ncbi.nlm.nih.gov/pubmed/20620998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.05.002
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